欧盟评估大肠杆菌DSM 34232生产的L-胱氨酸作为所有动物饲料添加剂的安全性和有效性

　　食品伙伴网讯  2025年10月17日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就大肠杆菌DSM 34232生产的L-胱氨酸（L-cystine）作为所有动物饲料添加剂的安全性和有效性发表科学意见。

 

　　经过评估，专家小组认为在建议的使用条件下该添加剂对目标物种、消费者和环境是安全的。由于其在饲料中的功能与在食品中的功能基本相同，因此认为没有必要进一步证明其功效。部分原文报道如下：

 

　　Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of l-cystine produced with a genetically modified strain of Escherichia coli K-12 (DSM 34232) as a sensory feed additive (functional group: flavouring compounds) for all animal species. The l-cystine manufactured by fermentation with E. coli DSM 34232 did not give rise to any safety concern regarding the genetic modification of the production strain. No viable cells or DNA of the production strain were detected in the final product. The use of l-cystine produced by fermentation with E. coli DSM 34232 in feed was considered safe for the target species when supplemented at concentrations up to 25 mg/kg complete feed. The FEEDAP Panel considered that the use of l-cystine in animal nutrition is safe for the consumers of products from animals receiving the additive, and for the environment. Regarding user safety, the additive was not considered a skin and eye irritant, nor a skin sensitiser. As l-cystine is used in food as a flavouring compound, it is expected that it can provide a similar function in feed and no further demonstration of efficacy is necessary.

 

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